hrp0092p1-421 | Thyroid (2) | ESPE2019

Zinc Transporter 8 (ZnT8) as a New Autoantigen in Thyroid Tissue – Preliminary Data

Bossowski Artur , Niklinska Wieslawa , Gasowska Marta , Polnik Dariusz , Szalecki Mieczyslaw , Miklosz Agnieszka , Chabowski Adrian , Reszec Joanna

Zinc (Zn) is a crucial trace mineral that regulates the expression and activation of biological molecules such as transcription factors, enzymes, adapters, channels, and growth factors, along with their receptors. Bioinformatics analysis of the human genome discloses that Zn may bind ~ 10% of all of the proteins found in the human organism. This remarkable finding highlights the physiological significance of Zn in molecules involved in cellular processes and thereby i...